News
CIEN participates in ADPD 2026 in Copenhagen starting today with a strong international scientific presence
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The CIEN Foundation (Center for Research in Neurological Diseases) is participating from today, March 17, in the international conference ADPD 2026, held in Copenhagen until March 21, bringing together leading experts in neurodegenerative diseases worldwide.
Throughout the conference, CIEN researchers will play a prominent role with multiple oral presentations and scientific posters focused on biomarkers, neuroimaging, and neuropathology in Alzheimer’s disease, Parkinson’s disease, Lewy body dementia, and frontotemporal dementia.
Key presentations by CIEN researchers
CIEN researchers will contribute to several international symposia:
- Cristina Sanchez Martin will open CIEN’s participation with a presentation on brain atrophy patterns and pTau-217 levels (March 17).
- Linda Zhang will present findings on grey matter diffusivity and plasma biomarkers (March 18) and will also present two posters on %p-tau217 as a predictor of cognitive decline.
- Mario Ricciardi Serra will present a neuropathological study on cerebral amyloid angiopathy (March 18).
- Orfeas Vourkas will present comparative results between MRI and FDG-PET in tau-related neurodegeneration (March 21).
- Michel J. Grothe will present a study on brain-wide atrophy patterns associated with hippocampal sclerosis (March 21).
Strong presence in poster sessions
CIEN will also have a strong presence in poster sessions, including:
- Contributions led by Jesús Silva-Rodríguez, focusing on %p-tau217 and other plasma biomarkers as predictors of long-term cognitive decline and clinical progression.
- Additional studies led by Minerva Martinez-Castillo, Sonia Wagner-Reguero, Elizabeth Valeriano-Lorenzo, and Maria Ascensión Zea-Sevilla, covering Lewy pathology biomarkers, α-synuclein diagnostic techniques, GFAP modulation, and the development of a frontotemporal dementia cohort.
Advancing biomarkers and precision medicine
CIEN’s contributions highlight advances in blood-based biomarkers, particularly %p-tau217, and their ability to predict disease progression in preclinical stages.
The research also emphasizes the integration of neuroimaging and biomarker data, supporting the development of new diagnostic tools and advancing precision medicine approaches in neurodegenerative diseases.
CIEN’s participation in ADPD 2026 reinforces its role as an international leader in translational research, contributing to progress in early diagnosis, patient stratification, and the development of new therapeutic strategies.
CIEN Researchers Contributions at ADPD 2026
| Presenter | Type | Title / Abstract | Date | Time/Shift | Room | Authors |
|---|---|---|---|---|---|---|
| Cristina Sanchez Martin | Oral Presentation | Baseline and Long-Term Longitudinal Atrophy Patterns of Cognitively Unimpaired Individuals with Elevated Levels of Plasma pTau-217 (ID 881) | 17/03/2026 | 14:30–14:45 | Auditorium 10+11 | Cristina Sanchez Martin, Linda Zhang, Jesús Silva-Rodriguez, Elizabeth L. Valeriano-Lorenzo, Francisco J. López-González, Sonia Wagner, Teodoro Del Ser, Pascual Sanchez-Juan, Michel J. Grothe |
| Linda Zhang | Oral Presentation | Mean Diffusivity in MTL Grey Matter is More Sensitive to Plasma %pTau217 Levels than in White Matter in a Cognitively Unimpaired Cohort (ID 1725) | 18/03/2026 | 09:25–09:40 | Auditorium 12 | Linda Zhang, Jesús Silva-Rodriguez, Eva Alfayate, Sonia Wagner-Reguero, Pascual Sanchez-Juan, Michel J. Grothe |
| Mario Ricciardi Serra | Oral Presentation | Neuropathological Assessment of the Boston Criteria v2.0 for Diagnosing Cerebral Amyloid Angiopathy in AD Dementia (ID 347) | 18/03/2026 | 17:00–17:15 | Auditorium 12 | Mario Ricciardi Serra, Iván Burgueño-García, Lucia Valeriano-Lorenzo, Maria Ascensión Zea-Sevilla, Meritxell Valentí, María Belen Frades Payo, Isabel López, Francisco J. López-González, Paloma Ruiz, Laura Saiz, Alicia Uceda Heras, Linda Zhang, Mabel Torres Llacsa, Eva Alfayate Sáez, Marta Molero-Cartón, María José López-Martínez, Teodoro Del Ser, Michel J. Grothe, Alberto Rábano-Gutiérrez, Pascual Sanchez-Juan |
| Michel J. Grothe | Oral Presentation | Characterizing the Brain-Wide Atrophy Pattern of Late-NC-Associated Hippocampal Sclerosis (ID 1295) | 21/03/2026 | 17:00–17:15 | Auditorium 10 | Michel J. Grothe, Linda Zhang, Francisco J. López-González, Pascual Sanchez-Juan, Alberto Rábano-Gutiérrez, Jesús Silva-Rodriguez |
| Orfeas Vourkas | Oral Presentation | Stage- and Region-Specific Differences Between MRI and FDG-PET for Tracking Tau-Related Neurodegeneration (ID 349) | 21/03/2026 | 14:40–14:55 | Auditorium 15 | Orfeas Vourkas, Linda Zhang, Alberto Rábano-Gutiérrez, Pascual Sanchez-Juan, Jesús Silva-Rodriguez, Michel J. Grothe |
| Jesús Silva-Rodriguez | Poster | Plasma %p-Tau217 Predicts Long-Term Cognitive Decline (ID 1745) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Jesús Silva-Rodriguez, Linda Zhang, Luca Kleineidam, Sonia Wagner, Francisco J. López-González, Cristina Sanchez Martin, Lucia Valeriano-Lorenzo, Teodoro Del Ser, Michel J. Grothe, Pascual Sanchez-Juan |
| Jesús Silva-Rodriguez | Poster | Head-to-Head Comparison of Plasma Biomarkers for Clinical Progression (ID 1752) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Jesús Silva-Rodriguez, Linda Zhang, Sonia Wagner, Francisco J. López-González, Lucia Valeriano-Lorenzo, Teodoro Del Ser, Michel J. Grothe, Pascual Sanchez-Juan |
| Minerva Martinez-Castillo | Poster | Uncovering Plasma Biomarkers for Lewy Pathology (ID 1340) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Minerva Martinez-Castillo, Sonia Wagner-Reguero, Iván Burgueño-García, Ana Belén Pastor, Paloma Ruiz-Valderrey, María José López-Martínez, Laura Saiz-Aúz, Pamela Martino-Adami, Alfredo Ramirez, Aitana Sogorb-Esteve, Alberto Rábano, Pascual Sanchez-Juan |
| Sonia Wagner-Reguero | Poster | α-Synuclein Aggregation RT-QuIC as a Tool for Post-Mortem Molecular Diagnosis of Synucleinopathies (ID 1471) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Sonia Wagner-Reguero, Sezgi Canaslan, Minerva Martinez-Castillo, Inga Zerr, Maria José Martínez-López, Iván Burgueño-García, Alberto Rábano-Gutiérrez, Aitana Sogorb-Esteve, Pascual Sanchez-Juan |
| Elizabeth Valeriano-Lorenzo | Poster | Astroglia Modulatory Effect of GFAP on the Association Between Plasma p-Tau217 Levels and Cognitive Decline (ID 2112) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Elizabeth Valeriano-Lorenzo, Mario Ricciardi Serra, Sonia Wagner, Minerva Martinez-Castillo, María Belen Frades Payo, Maria Ascensión Zea-Sevilla, Meritxell Valentí, Teodoro Del Ser, Pascual Sanchez-Juan |
| Elizabeth Valeriano-Lorenzo | Poster | Madrid-Frontotemporal Dementia Cohort for the Validation of Cutting-Edge Biomarkers (ID 851) | 19/03/2026-21/03/2026 | Shift 2 | Poster Session Area | Maria Ascensión Zea-Sevilla, Madrid-Frontotemporal Dementia Consortium, María Belen Frades Payo, Lucia Valeriano-Lorenzo, Isabel López, Francisco J. López-González, Sonia Wagner, Ana Belén Pastor, Nekane Manzano, Minerva Martinez-Castillo, Eva Alfayate, Marta Molero, Marta Anton, Meritxell Valentí, Mario Ricciardi Serra, Alberto Rábano-Gutiérrez, Michel J. Grothe, Teodoro Del Ser, Pascual Sanchez-Juan |