CIEN Neuropathology‑Biobank Platform at the 13th European Congress of Neuropathology (ECNP 2025)
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From June 11 to 14, 2025, a team from the CIEN Neuropathology‑Biobank Platform attended the 13th European Congress of Neuropathology (ECNP 2025), held in Maastricht (The Netherlands). Organized under the theme “Knowing the Past, Looking to the Future,” the congress brought together international experts in neuropathology to share the latest advances in the field of neurological diseases, in both in-person and virtual formats.
The CIEN team presented several studies showcasing progress in understanding neurodegenerative diseases and dementia-related brain pathology:
In advanced age dementia patients, hippocampal sclerosis without LATE display predominantly early stages of HS and low vascular scores
- Formato: Flash Talk and Poster
- Presentado por: Alicia Uceda‑Heras
- Autores: Iván Burgueño‑García, Alicia Uceda‑Heras, Paloma Ruiz‑Valderrey, Laura Saiz‑Aúz, María José López‑Martínez, Alberto Rábano
- Resumen: This study analyzes dementia cases in advanced age showing hippocampal sclerosis (HS) in the absence of limbic-predominant age-related TDP-43 encephalopathy (LATE), revealing mostly early HS stages and low vascular pathology.
Neuropathological Insights into Progressive Supranuclear Palsy: The Interplay of Combined Proteinopathies
- Formato:Póster
- Presentado por: María José López‑Martínez
- Autores: María José López‑Martínez, Laura Saiz‑Aúz, Paloma Ruiz‑Valderrey, Iván Burgueño‑García, Alicia Uceda‑Heras, Alberto Rábano
- Resumen: This study explores the presence and impact of co-occurring proteinopathies in progressive supranuclear palsy (PSP), offering new insights into the neuropathological heterogeneity of the disease.
Decoding GFAP in Dementia: A Focus on the Medial Temporal Lobe
- Formato: Póster
- Presentado por: Alicia Uceda‑Heras
- Autores: Alicia Uceda‑Heras, Iván Burgueño‑García, Paloma Ruiz‑Valderrey, Laura Saiz‑Aúz, María José López‑Martínez, Alberto Rábano
- Resumen: This work investigates the role of glial fibrillary acidic protein (GFAP) as a potential neuropathological biomarker in dementia, focusing on changes in the medial temporal lobe.
We are grateful for the opportunity to share our findings with the international scientific community and to continue contributing to neuropathological knowledge in the field of dementia.
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