Page 12 - Memora anual Fundación CIEN 2015
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1.3. Letter from the Manager of the CIEN Foundation

                                                        ople within CIEN Foundation, this would not be pos-
                                                        sible.

                                                        At CIEN Foundation we conceive research as a ap-
                                                        plied model that allows us to translate progress in a
                                                        benefit to society. Research should be a shaft ge-
                                                        nerating innovation. In this regard, this year CIEN
                                                        Foundation has collaborated as co-owner in three
                                                        patent applications, both national and international.

                                                        Among the activities launched in previous years
                                                        highlights the Vallecas project, one of the most am-
                                                        bitious studies being developed in Spain to advance
                                                        the early diagnosis of Alzheimer's disease. In 2015,
                                                        some of the 1,213 volunteers who selflessly partici-
                                                        pate in the project underwent the fifth follow-up visit.
                                                        Currently, the third, fourth and fifth follow-up visits are
                                                        being carried out simultaneously.

One more year is a pleasure for me to address you to    The Vallecas Project has also begun to bear fruit. Our
review the activities undertaken by the Center for      researchers have published in the journal Frontiers in
Research in Neurological Diseases (CIEN, for its        Aging Neuroscience an article describing the ob-
acronym in Spanish) Foundation during the year just     jectives and the methodology used in the study. This
ended.                                                  article is included among the 46 scientific publica-
                                                        tions produced in 2015, among which also highlights
2015 could be defined as a consolidation period of      the publication in the journal Alzheimers & Demen-
actions initiated in prior years and of future projec-  tia, which has led to the first high impact publication
tion, always aligned with the principal axes that       based on data from clinical-pathological correlation
have marked our progress in recent years: commit-       from Vallecas Alzheimer Center Research Program
ment to a model of translational research and inter-    (PICAV, from its acronym in Spanish). During 2016 it is
nationalization of our project. Without the constant    planned to publish new work in which the first fin-
support provided by the Queen Sofia Foundation for      dings of the project will be presented Vallecas.
a decade now and without the commitment of pe-
                                                        At the end of the year has concluded the recruit-
                                                        ment of participants in the new multicenter research
                                                        project led by CIEN Foundation, in collaboration with
                                                        Alzheimer Leon and Alzheimer Soria associations: de-
                                                        tection of TAU protein in tears as a possible biomar-
                                                        ker of Alzheimer’s disease. During 2016, professionals
                                                        from the Center for Molecular Biology Severo Ochoa
                                                        will analyze the 100 samples that have been collec-
                                                        ted.

María Ángeles Pérez Muñoz
Manager of the CIEN Foundation
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